Version 5.4
Homo sapiens Protein: FCER2
Summary
InnateDB Protein IDBP-761057.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCER2
Protein Name
Synonyms BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF;
Species Homo sapiens
Ensembl Protein ENSP00000471974
InnateDB Gene IDBG-23316 (FCER2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 6 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005178 integrin binding
GO:0019863 IgE binding
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
Biological Process
GO:0007219 Notch signaling pathway
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0051712 positive regulation of killing of cells of other organism
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P06734
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 2208
UniGene Hs.465778
RefSeq
HUGO HGNC:3612
OMIM 151445
CCDS CCDS12184
HPRD 01049
IMGT
EMBL AC008763 BC014108 BC062591 M14766 M15059 M23562 X04772
GenPept AAA52433 AAA52434 AAA52435 AAH14108 AAH62591 CAA28465

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca