InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SHPK

Summary

InnateDB Protein

IDBP-761191.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SHPK

Protein Name

Synonyms

CARKL; SHK; VR1;

Species

Homo sapiens

Ensembl Protein

ENSP00000459962

InnateDB Gene

IDBG-727056 (SHPK)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005216	ion channel activity
GO:0005231	excitatory extracellular ligand-gated ion channel activity
GO:0005262	calcium channel activity
GO:0005515	protein binding
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0015278	calcium-release channel activity
GO:0051219	phosphoprotein binding

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0007166	cell surface receptor signaling pathway
GO:0007635	chemosensory behavior
GO:0034220	ion transmembrane transport
GO:0050955	thermoception
GO:0055085	transmembrane transport
GO:0070588	calcium ion transmembrane transport
GO:0071312	cellular response to alkaloid
GO:0071318	cellular response to ATP

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0030054	cell junction
GO:0031226	intrinsic component of plasma membrane
GO:0032591	dendritic spine membrane
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002110 Ankyrin repeat
IPR004729 Transient receptor potential channel
IPR008347 Transient receptor potential channel, vanilloid 1-4
IPR020683 Ankyrin repeat-containing domain

PFAM

PF00023
PF13606
PF11929
PF12796

PRINTS

PR01415
PR01768

PIRSF

SMART

SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt