Version 5.4
Homo sapiens Protein: NLRP4
Summary
InnateDB Protein IDBP-761688.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NLRP4
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000465463
InnateDB Gene IDBG-71189 (NLRP4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
Biological Process
GO:0006954 inflammatory response
GO:0032479 regulation of type I interferon production
GO:0032481 positive regulation of type I interferon production
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003590 Leucine-rich repeat, ribonuclease inhibitor subtype
IPR007111 NACHT nucleoside triphosphatase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM
PRINTS
PIRSF
SMART SM00368
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96MN2
PhosphoSite PhosphoSite-Q96MN2
TrEMBL
UniProt Splice Variant
Entrez Gene 147945
UniGene Hs.631533
RefSeq
HUGO HGNC:22943
OMIM 609645
CCDS
HPRD 09619
IMGT
EMBL AF442488 AF479747 AF482706 AK056688 AY072792 BC016443 BC050326
GenPept AAH16443 AAH50326 AAL35293 AAL68396 AAL87104 AAL88672 BAB71254

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca