InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FDXR

Summary

InnateDB Protein

IDBP-762513.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDXR

Protein Name

Synonyms

ADXR;

Species

Homo sapiens

Ensembl Protein

ENSP00000462183

InnateDB Gene

IDBG-67702 (FDXR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	2 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004324	ferredoxin-NADP+ reductase activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity

Biological Process

GO:0006091	generation of precursor metabolites and energy
GO:0006694	steroid biosynthetic process
GO:0008203	cholesterol metabolic process
GO:0044281	small molecule metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix

Protein Structure and Domains

PDB ID

InterPro

IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF07992

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P22570

PhosphoSite

PhosphoSite-P22570

TrEMBL

UniProt Splice Variant

Entrez Gene

2232

UniGene

Hs.69745

RefSeq

NP_001244943

HUGO

HGNC:3642

OMIM

103270

CCDS

CCDS58592

HPRD

00060

IMGT

EMBL

AC068874 AK293208 AK295307 AK298908 AK301779 AK301977 BC002960 DQ085780 J03826 M58508 M58509

GenPept

AAA51668 AAA51669 AAB59497 AAB59498 AAH02960 AAY68215 BAG56748 BAG58287 BAG61016 BAG63236 BAH13598