InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: POLR2A

Summary

InnateDB Protein

IDBP-762613.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

POLR2A

Protein Name

Synonyms

hRPB220; hsRPB1; POLR2; POLRA; RPB1; RPBh1; RpIILS; RPO2; RPOL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000461879

InnateDB Gene

IDBG-25255 (POLR2A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 435 experimentally validated interaction(s) in this database.
They are also associated with 27 interaction(s) predicted by orthology.

Experimentally validated
Total	435 [view]
Protein-Protein	304 [view]
Protein-DNA	131 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	27 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003899	DNA-directed RNA polymerase activity

Biological Process

GO:0006351

transcription, DNA-templated

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000722 RNA polymerase, alpha subunit
IPR006592 RNA polymerase, N-terminal
IPR007066 RNA polymerase Rpb1, domain 3
IPR007080 RNA polymerase Rpb1, domain 1

PFAM

PF00623
PF04983
PF04997

PRINTS

PIRSF

SMART

SM00663

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite