InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAD23A

Summary

InnateDB Protein

IDBP-762975.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAD23A

Protein Name

Synonyms

HHR23A; HR23A;

Species

Homo sapiens

Ensembl Protein

ENSP00000467024

InnateDB Gene

IDBG-31509 (RAD23A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 162 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	162 [view]
Protein-Protein	162 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003684	damaged DNA binding
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0031593	polyubiquitin binding
GO:1990381	ubiquitin-specific protease binding

Biological Process

GO:0006289	nucleotide-excision repair
GO:0006974	cellular response to DNA damage stimulus
GO:0016032	viral process
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045070	positive regulation of viral genome replication
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR000626 Ubiquitin-like
IPR004806 UV excision repair protein Rad23
IPR006636 Heat shock chaperonin-binding
IPR009060 UBA-like
IPR015360 XPC-binding domain
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
IPR022617 Rad60/SUMO-like domain
IPR029071 Ubiquitin-related domain

PFAM

PF00627
PF00240
PF14560
PF09280
PF11976

PRINTS

PR01839

PIRSF

SMART

SM00213
SM00727
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt