Version 5.4
Homo sapiens Protein: MARCH2
Summary
InnateDB Protein IDBP-763234.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MARCH2
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000471536
InnateDB Gene IDBG-24762 (MARCH2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0006897 endocytosis
GO:0016567 protein ubiquitination
Cellular Component
GO:0005765 lysosomal membrane
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0010008 endosome membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
Protein Structure and Domains
PDB ID
InterPro IPR001841 Zinc finger, RING-type
IPR011016 Zinc finger, RING-CH-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF12906
PF00097
PRINTS
PIRSF
SMART SM00184
SM00744
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P0N8
PhosphoSite PhosphoSite-
TrEMBL M0R1P2
UniProt Splice Variant
Entrez Gene 51257
UniGene Hs.631861
RefSeq XP_006722825
HUGO HGNC:28038
OMIM 613332
CCDS CCDS12202
HPRD 14361
IMGT
EMBL AB197929 AC136469 AF151074 BC015910 BC032624 BC111388
GenPept AAF36160 AAH15910 AAH32624 AAI11389 BAD89359

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca