Version 5.4
Homo sapiens Protein: H3F3B
Summary
InnateDB Protein IDBP-763805.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H3F3B
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000466020
InnateDB Gene IDBG-68902 (H3F3B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.
Experimentally validated
Total 27 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
GO:0006336 DNA replication-independent nucleosome assembly
GO:0007596 blood coagulation
GO:0030307 positive regulation of cell growth
Cellular Component
GO:0000228 nuclear chromosome
GO:0000786 nucleosome
GO:0000788 nuclear nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0043234 protein complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000164 Histone H3/CENP-A
IPR007125 Histone core
IPR009072 Histone-fold
PFAM PF00125
PRINTS PR00622
PIRSF
SMART SM00428
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P84243
PhosphoSite PhosphoSite-P84243
TrEMBL V9H1G0
UniProt Splice Variant
Entrez Gene 3021
UniGene Hs.732048
RefSeq
HUGO HGNC:4765
OMIM 601128
CCDS CCDS11729
HPRD 03036
IMGT
EMBL AC087289 AF218029 AK304607 AK311905 AL512343 BC001124 BC006497 BC012813 BC017558 BC029405 BC038989 BC066901 BC067757 BC081560 BC081561 BC095447 BC108701 BX537379 CH471098 CH471099 M11353 M11354 V00521 X05855 X05856 X05857 Z48950
GenPept AAA52653 AAA52654 AAG17271 AAH01124 AAH06497 AAH12813 AAH17558 AAH29405 AAH38989 AAH81560 AAH81561 AAH95447 AAI08702 BAG34846 BAG65392 CAA23780 CAA29288 CAA88778 CAD97621 CAH73371 CAH73372 EAW69770 EAW69771 EAW69772 EAW69773 EAW89317 EAW89318 EAW89319

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca