Version 5.4
Homo sapiens Protein: EPS15L1
Summary
InnateDB Protein IDBP-763916.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPS15L1
Protein Name
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000471981
InnateDB Gene IDBG-35513 (EPS15L1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000261 EPS15 homology (EH)
IPR002048 EF-hand domain
IPR009053 Prefoldin
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00027
SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UBC2
PhosphoSite PhosphoSite-Q9UBC2
TrEMBL Q69YZ4
UniProt Splice Variant
Entrez Gene 58513
UniGene Hs.742093
RefSeq XP_006722888
HUGO HGNC:24634
OMIM
CCDS CCDS58653
HPRD 09445
IMGT
EMBL AB015346 AC008764 AC020917 AF110265 AK024166 AK296473 AL110270 BC131590 BC142716 CH471106
GenPept AAF21930 AAI31591 AAI42717 BAA88118 BAG51266 BAG59115 CAH10724 EAW84542 EAW84543

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca