Version 5.4
Homo sapiens Gene: EPS15L1
Summary
InnateDB Gene IDBG-35513.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPS15L1
Gene Name epidermal growth factor receptor pathway substrate 15-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000127527
Encoded Proteins
IDBP-35515
epidermal growth factor receptor pathway substrate 15-like 1
IDBP-374931
epidermal growth factor receptor pathway substrate 15-like 1
IDBP-591660
epidermal growth factor receptor pathway substrate 15-like 1
IDBP-760134
IDBP-761159
IDBP-761433
IDBP-761222
IDBP-765573
IDBP-763916
IDBP-765910
IDBP-765740
IDBP-766266
IDBP-766142
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:16355239-16472085
Strand Reverse strand
Band p13.11
Transcripts
ENST00000248070 ENSP00000248070
ENST00000455140 ENSP00000393313
ENST00000535753 ENSP00000440103
ENST00000599790 ENSP00000473242
ENST00000595845
ENST00000596037 ENSP00000472135
ENST00000597559
ENST00000592031 ENSP00000465286
ENST00000597937 ENSP00000472267
ENST00000596151
ENST00000594975 ENSP00000471662
ENST00000602022 ENSP00000471981
ENST00000594851 ENSP00000469495
ENST00000602009 ENSP00000472771
ENST00000593760 ENSP00000472958
ENST00000602151 ENSP00000468866
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0006897 endocytosis
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0016020 membrane
GO:0030132 clathrin coat of coated pit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000006276
View Gene Order
ENSBTAG00000009990
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_12484
EGFR downregulation pathway
REACT_9417
Signaling by EGFR pathway
REACT_115871
Signaling by EGFR in Cancer pathway
REACT_111102
Signal Transduction pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654639 Hs.658372 Hs.742093
RefSeq NM_001258374 NM_001258375 NM_001258376 NM_021235 XM_006722826
HUGO
OMIM
CCDS CCDS32944 CCDS58653 CCDS58654 CCDS59363
HPRD 09445
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca