Version 5.4
Homo sapiens Protein: BECN1
Summary
InnateDB Protein IDBP-764064.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BECN1
Protein Name
Synonyms ATG6; beclin1; VPS30;
Species Homo sapiens
Ensembl Protein ENSP00000465364
InnateDB Gene IDBG-51769 (BECN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 144 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 144 [view]
Protein-Protein 137 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 1 [view]
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000910 cytokinesis
GO:0006914 autophagy
GO:0006968 cellular defense response
GO:0016032 viral process
GO:0043066 negative regulation of apoptotic process
GO:0045087 innate immune response (InnateDB)
GO:0051607 defense response to virus
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002848 Translin
IPR007243 Atg6/Beclin
PFAM PF01997
PF04111
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14457
PhosphoSite PhosphoSite-Q14457
TrEMBL K7EQQ7
UniProt Splice Variant
Entrez Gene 8678
UniGene
RefSeq XP_005257815
HUGO HGNC:1034
OMIM 604378
CCDS CCDS11441
HPRD 05087
IMGT
EMBL AC016889 AF077301 AF139131 AK299616 AK312651 BC010276 CH471152 L38932
GenPept AAB59573 AAC68653 AAD27650 AAH10276 BAG35534 BAG61544 EAW60889 EAW60890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca