InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RAD51D

Summary

InnateDB Protein

IDBP-764633.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RAD51D

Protein Name

Synonyms

BROVCA4; R51H3; RAD51L3; TRAD;

Species

Homo sapiens

Ensembl Protein

ENSP00000466399

InnateDB Gene

IDBG-41136 (RAD51D)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.

Experimentally validated
Total	25 [view]
Protein-Protein	25 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000400	four-way junction DNA binding
GO:0003677	DNA binding
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity
GO:0043015	gamma-tubulin binding

Biological Process

GO:0000723	telomere maintenance
GO:0000724	double-strand break repair via homologous recombination
GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0007131	reciprocal meiotic recombination
GO:0042148	strand invasion

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005634	nucleus
GO:0005657	replication fork
GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex

Protein Structure and Domains

PDB ID

InterPro

IPR003593 AAA+ ATPase domain
IPR013632 DNA recombination and repair protein Rad51, C-terminal
IPR014774 Circadian clock protein KaiC/DNA repair protein RadA
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF08423
PF06745

PRINTS

PIRSF

SMART

SM00382

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O75771