InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADAMTS10

Summary

InnateDB Protein

IDBP-765253.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADAMTS10

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000471851

InnateDB Gene

IDBG-25135 (ADAMTS10)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	14 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0004222	metalloendopeptidase activity
GO:0005515	protein binding
GO:0008233	peptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0008150	biological_process

Cellular Component

GO:0001527	microfibril
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

InterPro

IPR000884 Thrombospondin, type 1 repeat
IPR001590 Peptidase M12B, ADAM/reprolysin
IPR002870 Peptidase M12B, propeptide
IPR010294 ADAM-TS Spacer 1
IPR010909 PLAC
IPR013273 Peptidase M12B, ADAM-TS

PFAM

PF00090
PF01421
PF01562
PF05986
PF08686

PRINTS

PR01857

PIRSF

SMART

SM00209

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt