InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FFAR2

Summary

InnateDB Protein

IDBP-765287.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FFAR2

Protein Name

Synonyms

FFA2R; GPR43;

Species

Homo sapiens

Ensembl Protein

ENSP00000473159

InnateDB Gene

IDBG-44260 (FFAR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0008289	lipid binding

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0071398	cellular response to fatty acid

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0042995	cell projection

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR013312 G protein-coupled receptor 40-related receptor
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019426 7TM GPCR, serpentine receptor class v (Srv)

PFAM

PF00001
PF10323

PRINTS

PR00237
PR01904

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O15552

PhosphoSite

PhosphoSite-O15552

TrEMBL

C6KYL4

UniProt Splice Variant

Entrez Gene

2867

UniGene

Hs.248056

RefSeq

HUGO

HGNC:4501

OMIM

603823

CCDS

CCDS12461

HPRD

04824

IMGT

EMBL

AB378083 AC002511 AF024690 BC095535 BC096198 BC096199 BC096200 BC096201 EU432114

GenPept

AAB67886 AAB86713 AAH95535 AAH96198 AAH96199 AAH96200 AAH96201 ABY87913 BAH86809