InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LPAR2

Summary

InnateDB Protein

IDBP-765381.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LPAR2

Protein Name

Synonyms

EDG-4; EDG4; LPA-2; LPA2;

Species

Homo sapiens

Ensembl Protein

ENSP00000465280

InnateDB Gene

IDBG-40085 (LPAR2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0070915	lysophosphatidic acid receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0007202	activation of phospholipase C activity
GO:0007204	positive regulation of cytosolic calcium ion concentration

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030139	endocytic vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR001671 Melanocortin/ACTH receptor
IPR002277 Lysophosphatidic acid receptor EDG-2
IPR004061 Sphingosine 1-phosphate receptor
IPR004065 Lysophosphatidic acid receptor
IPR004066 Lysophosphatidic acid receptor EDG-4
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx

PFAM

PF00001
PF10320

PRINTS

PR00237
PR00534
PR01148
PR01523
PR01527
PR01528

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9HBW0