InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SPHK2

Summary

InnateDB Protein

IDBP-765877.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPHK2

Protein Name

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000471205

InnateDB Gene

IDBG-60754 (SPHK2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003951	NAD+ kinase activity
GO:0004143	diacylglycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008481	sphinganine kinase activity
GO:0017016	Ras GTPase binding

Biological Process

GO:0006665	sphingolipid metabolic process
GO:0006669	sphinganine-1-phosphate biosynthetic process
GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0008283	cell proliferation
GO:0016310	phosphorylation
GO:0030148	sphingolipid biosynthetic process
GO:0043066	negative regulation of apoptotic process
GO:0044281	small molecule metabolic process
GO:0046834	lipid phosphorylation