InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CIRBP

Summary

InnateDB Protein

IDBP-765949.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CIRBP

Protein Name

Synonyms

CIRP;

Species

Homo sapiens

Ensembl Protein

ENSP00000468788

InnateDB Gene

IDBG-14114 (CIRBP)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.

Experimentally validated
Total	52 [view]
Protein-Protein	52 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003730	mRNA 3'-UTR binding
GO:0005515	protein binding
GO:0030371	translation repressor activity
GO:0044822	poly(A) RNA binding
GO:0070181	SSU rRNA binding

Biological Process

GO:0009411	response to UV
GO:0034063	stress granule assembly
GO:0045727	positive regulation of translation
GO:0048255	mRNA stabilization

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0010494	cytoplasmic stress granule

Protein Structure and Domains

PDB ID

InterPro

IPR000504 RNA recognition motif domain
IPR003954 RNA recognition motif domain, eukaryote

PFAM

PF00076

PRINTS

PIRSF

SMART

SM00360
SM00361

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q14011

PhosphoSite

PhosphoSite-Q14011

TrEMBL

Q53XX5

UniProt Splice Variant

Entrez Gene

1153

UniGene

Hs.722274

RefSeq

XP_006722700

HUGO

HGNC:1982

OMIM

602649

CCDS

CCDS12059

HPRD

08375

IMGT

EMBL

AB451225 AB451348 AC004221 AC004258 AF021336 BC000403 BC000901 BT007210 CH471139 D78134

GenPept

AAC04895 AAC51787 AAH00403 AAH00901 AAP35874 BAA11212 BAG70039 BAG70162 EAW69520 EAW69523