Version 5.4
Homo sapiens Gene: CIRBP
Summary
InnateDB Gene IDBG-14114.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CIRBP
Gene Name cold inducible RNA binding protein
Synonyms CIRP
Species Homo sapiens
Ensembl Gene ENSG00000099622
Encoded Proteins
IDBP-14116
cold inducible RNA binding protein
IDBP-362034
cold inducible RNA binding protein
IDBP-362036
cold inducible RNA binding protein
IDBP-765830
IDBP-765762
IDBP-765118
IDBP-762265
IDBP-764157
IDBP-765949
IDBP-761095
IDBP-760085
IDBP-766154
IDBP-765525
IDBP-765042
IDBP-765175
IDBP-766168
IDBP-760991
IDBP-763922
IDBP-763272
IDBP-765790
IDBP-765774
IDBP-761483
IDBP-764224
IDBP-764972
IDBP-763124
IDBP-765818
IDBP-762364
IDBP-762280
IDBP-764117
IDBP-764504
IDBP-763870
IDBP-762935
IDBP-761727
IDBP-760837
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:1259384-1274880
Strand Forward strand
Band p13.3
Transcripts
ENST00000320936 ENSP00000322887
ENST00000444172 ENSP00000407512
ENST00000413636 ENSP00000412831
ENST00000592815 ENSP00000467028
ENST00000586636 ENSP00000464906
ENST00000593283
ENST00000591055 ENSP00000466216
ENST00000591935 ENSP00000467734
ENST00000585630 ENSP00000466110
ENST00000588030 ENSP00000468788
ENST00000590704
ENST00000590347 ENSP00000467307
ENST00000589266 ENSP00000467138
ENST00000591659 ENSP00000468097
ENST00000591376 ENSP00000464830
ENST00000592051 ENSP00000468016
ENST00000593128
ENST00000592412 ENSP00000467876
ENST00000593048 ENSP00000467791
ENST00000592234 ENSP00000466131
ENST00000587323 ENSP00000465077
ENST00000589235 ENSP00000467848
ENST00000588090 ENSP00000466207
ENST00000593093
ENST00000588917
ENST00000590171 ENSP00000464728
ENST00000586773 ENSP00000468645
ENST00000586548 ENSP00000466712
ENST00000589710 ENSP00000466897
ENST00000586555
ENST00000591097 ENSP00000468229
ENST00000589686 ENSP00000465334
ENST00000589161
ENST00000585914 ENSP00000467948
ENST00000587169 ENSP00000465114
ENST00000587896 ENSP00000466025
ENST00000591622
ENST00000586472 ENSP00000465779
ENST00000590188
ENST00000592467
ENST00000588411 ENSP00000465338
ENST00000588344 ENSP00000466238
ENST00000588230 ENSP00000465558
ENST00000585913 ENSP00000467449
ENST00000621399
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 52 experimentally validated interaction(s) in this database.
Experimentally validated
Total 52 [view]
Protein-Protein 52 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003730 mRNA 3'-UTR binding
GO:0005515 protein binding
GO:0030371 translation repressor activity
GO:0044822 poly(A) RNA binding
GO:0070181 SSU rRNA binding
Biological Process
GO:0009409 response to cold
GO:0009411 response to UV
GO:0017148 negative regulation of translation
GO:0034063 stress granule assembly
GO:0045727 positive regulation of translation
GO:0048255 mRNA stabilization
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0010494 cytoplasmic stress granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000045193
View Gene Order
ENSBTAG00000007480
Not yet available
Cross-References
SwissProt
TrEMBL K7EJV5 K7ELV6 K7EMY9 K7EPM4 K7EQX4
UniProt Splice Variant
Entrez Gene 1153
UniGene Hs.618145 Hs.634522 Hs.666520 Hs.722274
RefSeq NM_001280 NM_001300815 NM_001300829
HUGO HGNC:1982
OMIM 602649
CCDS CCDS74244 CCDS12059 CCDS74245
HPRD 08375
IMGT
EMBL AC004221 AC004258
GenPept
RNA Seq Atlas 1153

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca