InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: APC2

Summary

InnateDB Protein

IDBP-766082.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

APC2

Protein Name

Synonyms

APCL;

Species

Homo sapiens

Ensembl Protein

ENSP00000467073

InnateDB Gene

IDBG-14549 (APC2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0008017	microtubule binding

Biological Process

GO:0016055	Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0035414	negative regulation of catenin import into nucleus
GO:0090090	negative regulation of canonical Wnt signaling pathway

Cellular Component

GO:0000139	Golgi membrane
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005881	cytoplasmic microtubule
GO:0005884	actin filament
GO:0015630	microtubule cytoskeleton
GO:0016342	catenin complex
GO:0031258	lamellipodium membrane
GO:0048471	perinuclear region of cytoplasm