InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FBL

Summary

InnateDB Protein

IDBP-766269.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FBL

Protein Name

Synonyms

FIB; FLRN; RNU3IP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000472419

InnateDB Gene

IDBG-50843 (FBL)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 136 experimentally validated interaction(s) in this database.

Experimentally validated
Total	136 [view]
Protein-Protein	135 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0008168	methyltransferase activity
GO:0016429	tRNA (adenine-N1-)-methyltransferase activity

Biological Process

GO:0006364	rRNA processing
GO:0008033	tRNA processing
GO:0030488	tRNA methylation
GO:0032259	methylation

Cellular Component

GO:0031515

tRNA (m1A) methyltransferase complex

Protein Structure and Domains

PDB ID

InterPro

IPR000692 Fibrillarin
IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01269
PF08704

PRINTS

PR00052

PIRSF

PIRSF006540
PIRSF017269

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

M0R299

UniProt Splice Variant

Entrez Gene

2091

UniGene

Hs.626441

RefSeq

HUGO

HGNC:3599

OMIM

134795

CCDS

HPRD

00617

IMGT

EMBL

AC005393 AC006950

GenPept