InnateDB Protein
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IDBP-76733.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HDAC8
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Protein Name
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histone deacetylase 8
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000362655
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InnateDB Gene
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IDBG-76713 (HDAC8)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
96
[view]
|
Protein-Protein |
35
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
60
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
|
|
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Molecular Function |
Accession |
GO Term |
GO:0004407
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histone deacetylase activity
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GO:0008134
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transcription factor binding
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GO:0032041
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NAD-dependent histone deacetylase activity (H3-K14 specific)
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GO:0046872
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metal ion binding
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GO:0046969
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NAD-dependent histone deacetylase activity (H3-K9 specific)
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GO:0046970
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NAD-dependent histone deacetylase activity (H4-K16 specific)
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GO:0097372
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NAD-dependent histone deacetylase activity (H3-K18 specific)
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003084
Histone deacetylase
IPR023801
Histone deacetylase domain
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PFAM |
PF00850
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PRINTS |
PR01271
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PIRSF |
PIRSF037913
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BY41
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PhosphoSite |
PhosphoSite-Q9BY41
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
55869
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UniGene |
Hs.610708
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RefSeq |
NP_001159892
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HUGO |
HGNC:13315
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OMIM |
300269
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CCDS |
CCDS55450
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HPRD |
02227
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IMGT |
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EMBL |
AA376331
AF212246
AF230097
AF245664
AI159768
AJ277724
AK296641
AK300895
AL133500
BC050433
BQ189619
BX295542
T99283
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GenPept |
AAF73076
AAF73428
AAH50433
AAK14930
BAG59242
BAG62534
CAB90213
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