Version 5.4
Homo sapiens Protein: UPRT
Summary
InnateDB Protein IDBP-77379.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UPRT
Protein Name uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362481
InnateDB Gene IDBG-77377 (UPRT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:17384901}. Nucleus {ECO:0000269PubMed:17384901}.
Disease Associations
Tissue Specificity Highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. {ECO:0000269PubMed:17384901}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006222 UMP biosynthetic process
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0009116 nucleoside metabolic process
GO:0032868 response to insulin
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000836 Phosphoribosyltransferase domain
IPR029057 Phosphoribosyltransferase-like
PFAM PF00156
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96BW1
PhosphoSite PhosphoSite-Q96BW1
TrEMBL E9PSD7
UniProt Splice Variant
Entrez Gene 139596
UniGene Hs.614532
RefSeq NP_659489
HUGO HGNC:28334
OMIM 300656
CCDS CCDS14429
HPRD 06640
IMGT
EMBL AK056354 AK293024 AL137013 AL590234 AY643714 BC015116 CH471104 CR749336
GenPept AAH15116 AAT64916 BAF85713 CAH18190 CAI39681 CAI39682 CAI40088 CAI40089 EAW98631

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca