InnateDB Protein
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IDBP-7743.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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MFSD10
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Protein Name
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major facilitator superfamily domain containing 10
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Synonyms
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TETRAN; TETTRAN;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000347619
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InnateDB Gene
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IDBG-7739 (MFSD10)
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Protein Structure
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Function |
Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump. {ECO:0000269PubMed:17362938}.
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Subcellular Localization |
Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
Accession |
GO Term |
GO:0008493
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tetracycline transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR011701
Major facilitator superfamily
IPR016196
Major facilitator superfamily domain, general substrate transporter
IPR020846
Major facilitator superfamily domain
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PFAM |
PF07690
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q14728
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PhosphoSite |
PhosphoSite-Q14728
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10227
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UniGene |
Hs.632581
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RefSeq |
NP_001139541
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HUGO |
HGNC:16894
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OMIM |
610977
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CCDS |
CCDS3365
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HPRD |
10265
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IMGT |
|
EMBL |
AL390065
BC001502
BC014979
CH471131
L11669
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GenPept |
AAA36729
AAH01502
AAH14979
CAM21300
EAW82496
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