Version 5.4
Homo sapiens Gene: MFSD10
Summary
InnateDB Gene IDBG-7739.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MFSD10
Gene Name major facilitator superfamily domain containing 10
Synonyms TETRAN; TETTRAN
Species Homo sapiens
Ensembl Gene ENSG00000109736
Encoded Proteins
IDBP-7741
major facilitator superfamily domain containing 10
IDBP-7743
major facilitator superfamily domain containing 10
IDBP-480744
major facilitator superfamily domain containing 10
IDBP-479341
major facilitator superfamily domain containing 10
IDBP-474991
major facilitator superfamily domain containing 10
IDBP-478099
major facilitator superfamily domain containing 10
IDBP-475632
major facilitator superfamily domain containing 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein likely functions in efflux of organic anions, including the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:2930561-2934859
Strand Reverse strand
Band p16.3
Transcripts
ENST00000329687 ENSP00000332646
ENST00000355443 ENSP00000347619
ENST00000514800 ENSP00000426907
ENST00000514031
ENST00000503596 ENSP00000423509
ENST00000508221 ENSP00000425757
ENST00000507272 ENSP00000427637
ENST00000507555 ENSP00000423402
ENST00000508276
ENST00000512781
ENST00000509676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008493 tetracycline transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0006915 apoptotic process
GO:0015904 tetracycline transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000001082
View Gene Order
ENSBTAG00000021130
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.614319 Hs.632581
RefSeq NM_001120 NM_001146069 XM_005247927 XM_005247928
HUGO
OMIM
CCDS CCDS3365
HPRD 10265
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca