Version 5.4
Homo sapiens Protein: PIGT
Summary
InnateDB Protein IDBP-77646.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIGT
Protein Name phosphatidylinositol glycan anchor biosynthesis, class T
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000361774
InnateDB Gene IDBG-77636 (PIGT)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 10 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003923 GPI-anchor transamidase activity
GO:0005515 protein binding
Biological Process
GO:0006501 C-terminal protein lipidation
GO:0016255 attachment of GPI anchor to protein
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0042765 GPI-anchor transamidase complex
Protein Structure and Domains
PDB ID
InterPro IPR007245 GPI transamidase component PIG-T
PFAM PF04113
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969N2
PhosphoSite PhosphoSite-Q969N2
TrEMBL
UniProt Splice Variant
Entrez Gene 51604
UniGene Hs.437388
RefSeq NP_001171658
HUGO HGNC:14938
OMIM 610272
CCDS CCDS54465
HPRD 15136
IMGT
EMBL AB057724 AF132940 AK075469 AK225517 AK296139 AK302093 AL021578 AL121742 AY358588 BC015022 BC110892 BC136827 BC136828 BX537612 CH471077
GenPept AAD27715 AAH15022 AAI10893 AAI36828 AAI36829 AAQ88951 BAB60854 BAC11639 BAH12267 BAH13624 CAB57341 CAC18110 CAC36338 CAC36339 CAD97799 EAW75844 EAW75845 EAW75846

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca