Version 5.4
Homo sapiens Protein: SDPR
Summary
InnateDB Protein IDBP-77696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDPR
Protein Name serum deprivation response
Synonyms cavin-2; CAVIN2; PS-p68; SDR;
Species Homo sapiens
Ensembl Protein ENSP00000305675
InnateDB Gene IDBG-77694 (SDPR)
Protein Structure
UniProt Annotation
Function May play a role in targeting PRKCA to caveolae. {ECO:0000250UniProtKB:Q66H98}.
Subcellular Localization Cytoplasm, cytosol. Membrane, caveola. Note=Colocalizes with CAV1 to caveolae.
Disease Associations
Tissue Specificity Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. {ECO:0000269PubMed:10191091}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005901 caveola
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95810
PhosphoSite PhosphoSite-O95810
TrEMBL
UniProt Splice Variant
Entrez Gene 8436
UniGene Hs.595639
RefSeq NP_004648
HUGO HGNC:10690
OMIM 606728
CCDS CCDS2313
HPRD 09470
IMGT
EMBL AC098872 AF085481 BC016475
GenPept AAD17795 AAH16475 AAY24078

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca