Homo sapiens Gene: SDPR
Summary
InnateDB Gene IDBG-77694.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SDPR
Gene Name serum deprivation response
Synonyms cavin-2; CAVIN2; PS-p68; SDR
Species Homo sapiens
Ensembl Gene ENSG00000168497
Encoded Proteins
serum deprivation response
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:191834302-191847255
Strand Reverse strand
Band q32.3
Transcripts
ENST00000304141 ENSP00000305675
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001786 phosphatidylserine binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005901 caveola
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt O95810
TrEMBL
UniProt Splice Variant
Entrez Gene 8436
UniGene Hs.26530 Hs.595639
RefSeq NM_004657
HUGO HGNC:10690
OMIM 606728
CCDS CCDS2313
HPRD 09470
IMGT
EMBL AC098872 AF085481 BC016475
GenPept AAD17795 AAH16475 AAY24078
RNA Seq Atlas 8436