Version 5.4
Homo sapiens Protein: WFDC3
Summary
InnateDB Protein IDBP-77979.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol WFDC3
Protein Name WAP four-disulfide core domain 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000243938
InnateDB Gene IDBG-77977 (WFDC3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitously expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0030414 peptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR008197 Whey acidic protein-type 4-disulphide core
PFAM PF00095
PRINTS PR00003
PIRSF
SMART SM00217
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IUB2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 140686
UniGene Hs.645202
RefSeq NP_542181
HUGO HGNC:15957
OMIM
CCDS CCDS33478
HPRD 15676
IMGT
EMBL AF488306 AL050348 AL591713 BC102013 BC102014
GenPept AAI02014 AAI02015 AAN70993 CAC39444

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca