Homo sapiens Protein: CTSA
Summary
InnateDB Protein IDBP-78429.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTSA
Protein Name cathepsin A
Synonyms GLB2; GSL; NGBE; PPCA; PPGB;
Species Homo sapiens
Ensembl Protein ENSP00000361537
InnateDB Gene IDBG-78417 (CTSA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004180 carboxypeptidase activity
GO:0004185 serine-type carboxypeptidase activity
GO:0008047 enzyme activator activity
Biological Process
GO:0006508 proteolysis
GO:0006665 sphingolipid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0006886 intracellular protein transport
GO:0043085 positive regulation of catalytic activity
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0016020 membrane
GO:0043202 lysosomal lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001563 Peptidase S10, serine carboxypeptidase
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00450
PRINTS PR00724
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P10619
PhosphoSite PhosphoSite-P10619
TrEMBL U3KQ41
UniProt Splice Variant
Entrez Gene 5476
UniGene Hs.609336
RefSeq
HUGO HGNC:9251
OMIM 613111
CCDS CCDS46609
HPRD 02020
IMGT
EMBL AK312898 AL008726 BC000597 BC093009 M22960
GenPept AAA36476 AAH00597 AAH93009 BAG35745 CAA15501 CAI20248