Mus musculus Protein: Dlx5
Summary
InnateDB Protein IDBP-787904.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlx5
Protein Name distal-less homeobox 5
Synonyms AI385752;
Species Mus musculus
Ensembl Protein ENSMUSP00000138264
InnateDB Gene IDBG-128250 (Dlx5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
GO:0071837 HMG box domain binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0001958 endochondral ossification
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0008283 cell proliferation
GO:0030326 embryonic limb morphogenesis
GO:0030509 BMP signaling pathway
GO:0030855 epithelial cell differentiation
GO:0042472 inner ear morphogenesis
GO:0043583 ear development
GO:0045669 positive regulation of osteoblast differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048646 anatomical structure formation involved in morphogenesis
GO:0050679 positive regulation of epithelial cell proliferation
GO:0060021 palate development
GO:0060166 olfactory pit development
GO:0060322 head development
GO:0060325 face morphogenesis
GO:0060349 bone morphogenesis
GO:0071773 cellular response to BMP stimulus
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:101926
InterPro IPR022135 Distal-less-like homeobox protein, N-terminal domain
PFAM PF12413
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P70396
PhosphoSite PhosphoSite-P70396
TrEMBL
UniProt Splice Variant
Entrez Gene 13395
UniGene
RefSeq NP_942151
MGI ID
MGI Symbol Dlx5
OMIM
CCDS CCDS59691
HPRD
IMGT
EMBL AF022075 AF022076 AF022077 AF033011 AF072452 AF072453 U67840
GenPept AAB86899 AAB94580 AAB94581 AAB94582 AAC52843 AAF86636 AAF86637