InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tuba4a

Summary

InnateDB Protein

IDBP-788083.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tuba4a

Protein Name

tubulin, alpha 4A

Synonyms

M[a]4; Tuba4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140657

InnateDB Gene

IDBG-170381 (Tuba4a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.

Experimentally validated
Total	30 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	61 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007017	microtubule-based process
GO:0051258	protein polymerization

Cellular Component

GO:0005737	cytoplasm
GO:0005874	microtubule
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1095410

InterPro

IPR000217 Tubulin
IPR002452 Alpha tubulin
IPR002453 Beta tubulin
IPR002967 Delta tubulin
IPR003008 Tubulin/FtsZ, GTPase domain
IPR004057 Epsilon tubulin
IPR008280 Tubulin/FtsZ, C-terminal
IPR018316 Tubulin/FtsZ, 2-layer sandwich domain

PFAM

PF00091
PF03953

PRINTS

PR01161
PR01162
PR01163
PR01224
PR01519

PIRSF

SMART

SM00864
SM00865

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

22145

UniGene

RefSeq

NP_033473

MGI ID

MGI Symbol

Tuba4a

OMIM

CCDS

CCDS35623

HPRD

IMGT

EMBL

AK002427 AK078355 AK158934 BC019959 M13444

GenPept

AAA40502 AAH19959 BAB22094 BAC37234 BAE34732