Version 5.4
Mus musculus Protein: Glrx2
Summary
InnateDB Protein IDBP-788123.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Glrx2
Protein Name glutaredoxin 2 (thioltransferase)
Synonyms 1700010P22Rik; AI645710; Grx2;
Species Mus musculus
Ensembl Protein ENSMUSP00000141022
InnateDB Gene IDBG-196991 (Glrx2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0010033 response to organic substance
GO:0042542 response to hydrogen peroxide
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1916617
InterPro IPR002109 Glutaredoxin
IPR011899 Glutaredoxin, eukaryotic/virial
IPR012336 Thioredoxin-like fold
IPR014025 Glutaredoxin subgroup
PFAM PF00462
PF13098
PF13192
PF13462
PF13905
PRINTS PR00160
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3UQ95
UniProt Splice Variant
Entrez Gene 69367
UniGene
RefSeq NP_001033681
MGI ID
MGI Symbol Glrx2
OMIM
CCDS CCDS15343
HPRD
IMGT
EMBL AF276918 AF380337 AK005853 AK142654 BC132031 BC132033 BC145304
GenPept AAF86465 AAI32032 AAI32034 AAI45305 AAK85319 BAB24276 BAE25147

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca