Homo sapiens Protein: PCDH11X
Summary
InnateDB Protein IDBP-78836.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDH11X
Protein Name protocadherin 11 X-linked
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000362180
InnateDB Gene IDBG-78824 (PCDH11X)
Protein Structure
UniProt Annotation
Function Potential calcium-dependent cell-adhesion protein.
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. {ECO:0000269PubMed:10644456, ECO:0000269PubMed:11003707}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002126 Cadherin
IPR013164 Cadherin, N-terminal
IPR013585 Protocadherin
IPR015919 Cadherin-like
PFAM PF00028
PF08266
PF08374
PRINTS PR00205
PIRSF
SMART SM00112
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BZA7
PhosphoSite PhosphoSite-Q9BZA7
TrEMBL
UniProt Splice Variant
Entrez Gene 27328
UniGene Hs.655673
RefSeq NP_001161834
HUGO HGNC:8656
OMIM 300246
CCDS CCDS55461
HPRD 02215
IMGT
EMBL AB026187 AB037747 AC004388 AF206516 AF217288 AF332218 AF332219 AJ276804 AJ564931 AJ564932 AJ564933 AJ564934 AJ564935 AJ564936 AJ564942 AJ564945 AJ564946 AJ564947 AL121869 AL133274 AL133321 AY861432 AY861433 AY861434 AY861435
GenPept AAK13470 AAK13471 AAK82655 AAK82656 AAX56122 AAX56123 AAX56124 AAX56125 BAA90765 BAA92564 CAC13123 CAD92410 CAD92411 CAD92412 CAD92413 CAD92414 CAD92415 CAD92421 CAD92424 CAD92425 CAD92426 CAI41412 CAI41413 CAI41414 CAI41435 CAI41436 CAI41629 CAI41630 CAI41631