Homo sapiens Gene: PCDH11X
Summary
InnateDB Gene IDBG-78824.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCDH11X
Gene Name protocadherin 11 X-linked
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000102290
Encoded Proteins
protocadherin 11 X-linked
protocadherin 11 X-linked
protocadherin 11 X-linked
protocadherin 11 X-linked
protocadherin 11 X-linked
protocadherin 11 X-linked
protocadherin 11 X-linked
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with variable cytoplasmic domains. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:91779261-92623230
Strand Forward strand
Band q21.31
Transcripts
ENST00000361655 ENSP00000355105
ENST00000373097 ENSP00000362189
ENST00000373094 ENSP00000362186
ENST00000361724
ENST00000373088 ENSP00000362180
ENST00000298274
ENST00000395337 ENSP00000378746
ENST00000406881 ENSP00000384758
ENST00000504220 ENSP00000423762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.655673
RefSeq NM_001168360 NM_001168361 NM_001168362 NM_001168363 NM_032968 NM_032969
HUGO
OMIM
CCDS CCDS14461 CCDS14462 CCDS55458 CCDS55459 CCDS55460 CCDS55461
HPRD 02215
IMGT
EMBL
GenPept
RNA Seq Atlas