Version 5.4
Mus musculus Protein: Bdkrb1
Summary
InnateDB Protein IDBP-788479.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bdkrb1
Protein Name bradykinin receptor, beta 1
Synonyms B1BKR; B1R; Bdkrb; BKR1; BRADYB1;
Species Mus musculus
Ensembl Protein ENSMUSP00000138216
InnateDB Gene IDBG-169235 (Bdkrb1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004947 bradykinin receptor activity
GO:0042277 peptide binding
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0002687 positive regulation of leukocyte migration
GO:0006954 inflammatory response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0009612 response to mechanical stimulus
GO:0016477 cell migration
GO:0019233 sensory perception of pain
GO:0030308 negative regulation of cell growth
GO:0032496 response to lipopolysaccharide
GO:0045776 negative regulation of blood pressure
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0043005 neuron projection
Protein Structure and Domains
PDB ID MGI:88144
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000496 Bradykinin receptor family
IPR001186 Bradykinin receptor B1
IPR017452 GPCR, rhodopsin-like, 7TM
PFAM PF00001
PRINTS PR00237
PR00425
PR00993
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL S4R1G8
UniProt Splice Variant
Entrez Gene 12061
UniGene
RefSeq
MGI ID
MGI Symbol Bdkrb1
OMIM
CCDS
HPRD
IMGT
EMBL AC068459
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca