InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc8a3

Summary

InnateDB Protein

IDBP-788899.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc8a3

Protein Name

solute carrier family 8 (sodium/calcium exchanger), member 3

Synonyms

AW742262; Ncx3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138735

InnateDB Gene

IDBG-260476 (Slc8a3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005432	calcium:sodium antiporter activity
GO:0015368	calcium:cation antiporter activity

Biological Process

GO:0002244	hematopoietic progenitor cell differentiation
GO:0006814	sodium ion transport
GO:0006816	calcium ion transport
GO:0007154	cell communication
GO:0021537	telencephalon development
GO:0030001	metal ion transport
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport
GO:0060402	calcium ion transport into cytosol
GO:0071320	cellular response to cAMP
GO:1990034	calcium ion export from cell
GO:1990035	calcium ion import into cell

Cellular Component

GO:0005739	mitochondrion
GO:0005874	microtubule
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042383	sarcolemma
GO:0042995	cell projection
GO:0043025	neuronal cell body
GO:0043197	dendritic spine

Protein Structure and Domains

PDB ID

MGI:107976

InterPro

IPR003644 Na-Ca exchanger/integrin-beta4
IPR004836 Sodium/calcium exchanger protein
IPR004837 Sodium/calcium exchanger membrane region

PFAM

PF03160
PF01699

PRINTS

PR01259

PIRSF

SMART

SM00237

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

S4R2P9

UniProt Splice Variant

Entrez Gene

110893

UniGene

RefSeq

NP_536688

MGI ID

MGI Symbol

Slc8a3

OMIM

CCDS

CCDS36485

HPRD

IMGT

EMBL

AB080746 AC124384 AF321404

GenPept

AAG42826 BAB85835