InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rnf2

Summary

InnateDB Protein

IDBP-789224.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rnf2

Protein Name

ring finger protein 2

Synonyms

AI326319; AI450156; AU019207; dinG; Ring1B;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000140896

InnateDB Gene

IDBG-198115 (Rnf2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 161 experimentally validated interaction(s) in this database.
They are also associated with 96 interaction(s) predicted by orthology.

Experimentally validated
Total	161 [view]
Protein-Protein	154 [view]
Protein-DNA	7 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	96 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0016874	ligase activity
GO:0046872	metal ion binding
GO:0071535	RING-like zinc finger domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0000278	mitotic cell cycle
GO:0001702	gastrulation with mouth forming second
GO:0006351	transcription, DNA-templated
GO:0009948	anterior/posterior axis specification
GO:0016574	histone ubiquitination
GO:0036353	histone H2A-K119 monoubiquitination

Cellular Component

GO:0000151	ubiquitin ligase complex
GO:0000791	euchromatin
GO:0000792	heterochromatin
GO:0001739	sex chromatin
GO:0005634	nucleus
GO:0016604	nuclear body
GO:0031519	PcG protein complex
GO:0035102	PRC1 complex
GO:0071339	MLL1 complex