Version 5.4
Homo sapiens Protein: ZNF189
Summary
InnateDB Protein IDBP-78943.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZNF189
Protein Name zinc finger protein 189
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000363995
InnateDB Gene IDBG-78941 (ZNF189)
Protein Structure
UniProt Annotation
Function May be involved in transcriptional regulation.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 2 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF01352
PF00096
PRINTS
PIRSF
SMART SM00349
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O75820
PhosphoSite PhosphoSite-O75820
TrEMBL B7ZLK9
UniProt Splice Variant
Entrez Gene 7743
UniGene Hs.50123
RefSeq NP_001265161
HUGO HGNC:12980
OMIM 603132
CCDS CCDS65096
HPRD 11930
IMGT
EMBL AF025770 AF025771 AF025772 AK290163 AL353621 BC092425 BC126120 BC143876 BC143877 CH471105 U75454 U95991 U95992
GenPept AAC25909 AAC25910 AAC39798 AAC39799 AAC39800 AAD50527 AAD50528 AAH92425 AAI26121 AAI43877 AAI43878 BAF82852 CAI14611 CAI14612 CAI14613 EAW58949

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca