Version 5.4
Mus musculus Protein: Creb1
Summary
InnateDB Protein IDBP-789572.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Creb1
Protein Name cAMP responsive element binding protein 1
Synonyms 2310001E10Rik; 3526402H21Rik; AV083133; Creb; Creb-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000139995
InnateDB Gene IDBG-161359 (Creb1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
They are also associated with 181 interaction(s) predicted by orthology.
Experimentally validated
Total 36 [view]
Protein-Protein 22 [view]
Protein-DNA 14 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 181 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007409 axonogenesis
GO:0007595 lactation
GO:0007613 memory
GO:0008361 regulation of cell size
GO:0010033 response to organic substance
GO:0021983 pituitary gland development
GO:0030879 mammary gland development
GO:0033363 secretory granule organization
GO:0040018 positive regulation of multicellular organism growth
GO:0042493 response to drug
GO:0045672 positive regulation of osteoclast differentiation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0046887 positive regulation of hormone secretion
GO:0060428 lung epithelium development
GO:0060430 lung saccule development
GO:0060509 Type I pneumocyte differentiation
GO:0071294 cellular response to zinc ion
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:88494
InterPro IPR001630 cAMP response element binding (CREB) protein
IPR003102 Coactivator CBP, pKID
IPR004827 Basic-leucine zipper domain
IPR008917 Transcription factor, Skn-1-like, DNA-binding domain
PFAM PF02173
PF00170
PF07716
PRINTS PR00041
PIRSF
SMART SM00338
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q62347
UniProt Splice Variant
Entrez Gene 12912
UniGene
RefSeq
MGI ID
MGI Symbol Creb1
OMIM
CCDS CCDS15005
HPRD
IMGT
EMBL AC166336 AK044992 AK044993 CH466548 X92497
GenPept BAC32173 BAC32174 CAA63242 EDL00200

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca