Version 5.4
Mus musculus Protein: Clec7a
Summary
InnateDB Protein IDBP-789651.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clec7a
Protein Name C-type lectin domain family 7, member a
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000139167
InnateDB Gene IDBG-256772 (Clec7a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001846 opsonin binding
GO:0001872 (1->3)-beta-D-glucan binding
GO:0001874 (1->3)-beta-D-glucan receptor activity
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
Biological Process
GO:0001878 response to yeast
GO:0001879 detection of yeast
GO:0002238 response to molecule of fungal origin
GO:0002752 cell surface pattern recognition receptor signaling pathway
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0016337 single organismal cell-cell adhesion
GO:0032760 positive regulation of tumor necrosis factor production
GO:0050766 positive regulation of phagocytosis
Cellular Component
GO:0009897 external side of plasma membrane
Protein Structure and Domains
PDB ID MGI:1861431
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL V9GXI5
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
MGI ID
MGI Symbol Clec7a
OMIM
CCDS
HPRD
IMGT
EMBL AC138620
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca