InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tlr11

Summary

InnateDB Protein

IDBP-789704.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tlr11

Protein Name

toll-like receptor 11

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138814

InnateDB Gene

IDBG-156030 (Tlr11)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	1 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding

Biological Process

GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0006954	inflammatory response
GO:0007165	signal transduction
GO:0009617	response to bacterium
GO:0034170	toll-like receptor 11 signaling pathway
GO:0045087	innate immune response (InnateDB)
GO:0050707	regulation of cytokine secretion
GO:0050729	positive regulation of inflammatory response

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

MGI:3045226

InterPro

IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype

PFAM

PF01582
PF13676
PF00560
PF13504
PF13855

PRINTS

PIRSF

SMART

SM00255
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

V9GWT0

UniProt Splice Variant

Entrez Gene

239081

UniGene

RefSeq

MGI ID

MGI Symbol

Tlr11

OMIM

CCDS

CCDS27012

HPRD

IMGT

EMBL

AC135188 AY510704

GenPept

AAS37672