Version 5.4
Mus musculus Protein: Atg7
Summary
InnateDB Protein IDBP-790152.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atg7
Protein Name autophagy related 7
Synonyms 1810013K23Rik; Agp7; Apg7l; Atg7l; Gm21553;
Species Mus musculus
Ensembl Protein ENSMUSP00000138779
InnateDB Gene IDBG-178961 (Atg7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 16 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 2 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004839 ubiquitin activating enzyme activity
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001889 liver development
GO:0006497 protein lipidation
GO:0006520 cellular amino acid metabolic process
GO:0006914 autophagy
GO:0006996 organelle organization
GO:0007005 mitochondrion organization
GO:0007628 adult walking behavior
GO:0009791 post-embryonic development
GO:0016239 positive regulation of macroautophagy
GO:0016567 protein ubiquitination
GO:0021680 cerebellar Purkinje cell layer development
GO:0021860 pyramidal neuron development
GO:0021955 central nervous system neuron axonogenesis
GO:0021987 cerebral cortex development
GO:0030163 protein catabolic process
GO:0031175 neuron projection development
GO:0031396 regulation of protein ubiquitination
GO:0031401 positive regulation of protein modification process
GO:0032446 protein modification by small protein conjugation
GO:0039689 negative stranded viral RNA replication
GO:0042594 response to starvation
GO:0043066 negative regulation of apoptotic process
GO:0050877 neurological system process
GO:0055013 cardiac muscle cell development
GO:0061024 membrane organization
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1921494
InterPro IPR000594 UBA/THIF-type NAD/FAD binding fold
IPR006285 Ubiquitin-like modifier-activating enzyme Atg7
IPR009036 Molybdenum cofactor biosynthesis, MoeB
PFAM PF00899
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL S4R2T5
UniProt Splice Variant
Entrez Gene 74244
UniGene
RefSeq
MGI ID
MGI Symbol Atg7
OMIM
CCDS
HPRD
IMGT
EMBL AC122843 AC149276 AC170088
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca