InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Serpina1b

Summary

InnateDB Protein

IDBP-790378.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Serpina1b

Protein Name

serine (or cysteine) preptidase inhibitor, clade A, member 1B

Synonyms

D12Ucla2; Dom2; PI2; Spi1-2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000139941

InnateDB Gene

IDBG-167429 (Serpina1b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005515	protein binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006487	protein N-linked glycosylation
GO:0006953	acute-phase response
GO:0010951	negative regulation of endopeptidase activity
GO:0030162	regulation of proteolysis
GO:0034097	response to cytokine
GO:0043434	response to peptide hormone

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Protein Structure and Domains

PDB ID

MGI:891970

InterPro

IPR023796 Serpin domain

PFAM

PF00079

PRINTS

PIRSF

SMART

SM00093

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

20701

UniGene

RefSeq

MGI ID

MGI Symbol

Serpina1b

OMIM

CCDS

CCDS26138

HPRD

IMGT

EMBL

AF481949 BC022109 BC025445 BC049255 M25529 M75716

GenPept

AAA37132 AAC28865 AAH22109 AAH25445 AAH49255 AAM47489