Version 5.4
Mus musculus Gene: Serpina1b
Summary
InnateDB Gene IDBG-167429.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Serpina1b
Gene Name serine (or cysteine) preptidase inhibitor, clade A, member 1B
Synonyms D12Ucla2; Dom2; PI2; Spi1-2
Species Mus musculus
Ensembl Gene ENSMUSG00000071178
Encoded Proteins
IDBP-167431
serine (or cysteine) preptidase inhibitor, clade A, member 1B
IDBP-622331
serine (or cysteine) peptidase inhibitor, clade A, member 1A
IDBP-790378
serine (or cysteine) preptidase inhibitor, clade A, member 1B
IDBP-790379
serine (or cysteine) preptidase inhibitor, clade A, member 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:103728156-103830373
Strand Reverse strand
Band E
Transcripts
ENSMUST00000095450 ENSMUSP00000093101
ENSMUST00000164454 ENSMUSP00000127266
ENSMUST00000186166 ENSMUSP00000139941
ENSMUST00000187220 ENSMUSP00000141006
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006487 protein N-linked glycosylation
GO:0006953 acute-phase response
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
GO:0034097 response to cytokine
GO:0043434 response to peptide hormone
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_230203
Platelet degranulation pathway
REACT_224553
Hemostasis pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_206166
Response to elevated platelet cytosolic Ca2+ pathway
KEGG
mmu04610
Complement and coagulation cascades pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_009244
OMIM
CCDS CCDS26138
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca