Version 5.4
Mus musculus Protein: Dlg1
Summary
InnateDB Protein IDBP-790424.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlg1
Protein Name discs, large homolog 1 (Drosophila)
Synonyms B130052P05Rik; Dlgh1; E-dlg/SAP97; mKIAA4187; SAP-97; SAP97;
Species Mus musculus
Ensembl Protein ENSMUSP00000138782
InnateDB Gene IDBG-152959 (Dlg1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
They are also associated with 50 interaction(s) predicted by orthology.
Experimentally validated
Total 34 [view]
Protein-Protein 34 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 50 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0032947 protein complex scaffold
Biological Process
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001771 immunological synapse formation
GO:0002088 lens development in camera-type eye
GO:0002369 T cell cytokine production
GO:0008104 protein localization
GO:0008284 positive regulation of cell proliferation
GO:0030432 peristalsis
GO:0030838 positive regulation of actin filament polymerization
GO:0031579 membrane raft organization
GO:0031641 regulation of myelination
GO:0032147 activation of protein kinase activity
GO:0042110 T cell activation
GO:0042130 negative regulation of T cell proliferation
GO:0042391 regulation of membrane potential
GO:0042982 amyloid precursor protein metabolic process
GO:0048608 reproductive structure development
GO:0048704 embryonic skeletal system morphogenesis
GO:0048729 tissue morphogenesis
GO:0048745 smooth muscle tissue development
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051898 negative regulation of protein kinase B signaling
GO:0060022 hard palate development
Cellular Component
GO:0001772 immunological synapse
GO:0005605 basal lamina
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0016323 basolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0030054 cell junction
GO:0031253 cell projection membrane
GO:0031594 neuromuscular junction
GO:0045121 membrane raft
GO:0045202 synapse
Protein Structure and Domains
PDB ID MGI:107231
InterPro IPR001478 PDZ domain
IPR004172 L27
IPR015143 L27-1
IPR019583 PDZ-associated domain of NMDA receptors
IPR019590 Membrane-associated guanylate kinase (MAGUK), PEST domain, N-terminal
PFAM PF00595
PF13180
PF09058
PF10600
PF10608
PRINTS
PIRSF
SMART SM00228
SM00569
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL S4R2T8
UniProt Splice Variant
Entrez Gene 13383
UniGene
RefSeq
MGI ID
MGI Symbol Dlg1
OMIM
CCDS
HPRD
IMGT
EMBL AC126055 AC129214 AK220189 U51639
GenPept AAB18303 BAD90374

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca