InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ank2

Summary

InnateDB Protein

IDBP-790460.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ank2

Protein Name

ankyrin 2, brain

Synonyms

AI835472; Ank-2; AW491075;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138647

InnateDB Gene

IDBG-192780 (Ank2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0015459	potassium channel regulator activity

Biological Process

GO:0007165	signal transduction
GO:0008104	protein localization
GO:0033292	T-tubule organization
GO:0034613	cellular protein localization
GO:0042981	regulation of apoptotic process
GO:0060048	cardiac muscle contraction
GO:0072659	protein localization to plasma membrane
GO:0072661	protein targeting to plasma membrane
GO:0086036	regulation of cardiac muscle cell membrane potential
GO:2001257	regulation of cation channel activity

Cellular Component

GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0030018	Z disc
GO:0031430	M band
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:88025

InterPro

IPR000488 Death domain
IPR000906 ZU5
IPR002110 Ankyrin repeat
IPR011029 Death-like domain
IPR020683 Ankyrin repeat-containing domain

PFAM

PF00531
PF00791
PF00023
PF13606
PF11929
PF12796

PRINTS

PR01415

PIRSF

SMART

SM00005
SM00218
SM00248

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

S4R2H6

UniProt Splice Variant

Entrez Gene

109676

UniGene

RefSeq

XP_006500966

MGI ID

MGI Symbol

Ank2

OMIM

CCDS

HPRD

IMGT

EMBL

AC102480 AC102591 AC105163 AC113952 AC131744 AC157817

GenPept