InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ank2

Summary

InnateDB Protein

IDBP-790480.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ank2

Protein Name

ankyrin 2, brain

Synonyms

AI835472; Ank-2; AW491075;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000138089

InnateDB Gene

IDBG-192780 (Ank2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0015459	potassium channel regulator activity
GO:0019901	protein kinase binding
GO:0030507	spectrin binding
GO:0030674	protein binding, bridging
GO:0044325	ion channel binding
GO:0051117	ATPase binding

Biological Process

GO:0002027	regulation of heart rate
GO:0003283	atrial septum development
GO:0006874	cellular calcium ion homeostasis
GO:0008104	protein localization
GO:0010628	positive regulation of gene expression
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling
GO:0030913	paranodal junction assembly
GO:0031647	regulation of protein stability
GO:0033292	T-tubule organization
GO:0034394	protein localization to cell surface
GO:0034613	cellular protein localization
GO:0036309	protein localization to M-band
GO:0036371	protein localization to T-tubule
GO:0042981	regulation of apoptotic process
GO:0043268	positive regulation of potassium ion transport
GO:0050821	protein stabilization
GO:0051597	response to methylmercury
GO:0051924	regulation of calcium ion transport
GO:0051928	positive regulation of calcium ion transport
GO:0055117	regulation of cardiac muscle contraction
GO:0060048	cardiac muscle contraction
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization
GO:0070972	protein localization to endoplasmic reticulum
GO:0072659	protein localization to plasma membrane
GO:0072661	protein targeting to plasma membrane
GO:0086004	regulation of cardiac muscle cell contraction
GO:0086005	ventricular cardiac muscle cell action potential
GO:0086014	atrial cardiac muscle cell action potential
GO:0086015	SA node cell action potential
GO:0086036	regulation of cardiac muscle cell membrane potential
GO:0086066	atrial cardiac muscle cell to AV node cell communication
GO:0086070	SA node cell to atrial cardiac muscle cell communication
GO:0086091	regulation of heart rate by cardiac conduction
GO:1901018	positive regulation of potassium ion transmembrane transporter activity
GO:1901019	regulation of calcium ion transmembrane transporter activity
GO:1901021	positive regulation of calcium ion transmembrane transporter activity
GO:2001257	regulation of cation channel activity
GO:2001259	positive regulation of cation channel activity

Cellular Component

GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0014704	intercalated disc
GO:0016323	basolateral plasma membrane
GO:0016324	apical plasma membrane
GO:0030018	Z disc
GO:0030315	T-tubule
GO:0031430	M band
GO:0031672	A band
GO:0042383	sarcolemma
GO:0043005	neuron projection
GO:0043034	costamere
GO:0045121	membrane raft
GO:0045211	postsynaptic membrane
GO:0048471	perinuclear region of cytoplasm