InnateDB Protein
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IDBP-79416.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TRMT2B
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Protein Name
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TRM2 tRNA methyltransferase 2 homolog B (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000362027
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InnateDB Gene
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IDBG-79408 (TRMT2B)
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Protein Structure
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Function |
Probable S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNA. May also have a role in tRNA stabilization or maturation (By similarity). {ECO:0000250}.
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
Accession |
GO Term |
GO:0008168
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methyltransferase activity
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GO:0008173
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RNA methyltransferase activity
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GO:0030697
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S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007848
Methyltransferase small domain
IPR010280
(Uracil-5)-methyltransferase family
IPR029063
S-adenosyl-L-methionine-dependent methyltransferase-like
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PFAM |
PF05175
PF05958
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q96GJ1
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PhosphoSite |
PhosphoSite-Q96GJ1
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TrEMBL |
A0A024RCF5
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UniProt Splice Variant |
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Entrez Gene |
79979
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UniGene |
Hs.496501
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RefSeq |
NP_079193
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HUGO |
HGNC:25748
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OMIM |
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CCDS |
CCDS14477
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HPRD |
06520
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IMGT |
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EMBL |
AK022749
AL109952
AL133275
AL832849
BC007526
BC008067
BC009437
BC020116
BC034272
CH471115
Z97985
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GenPept |
AAH07526
AAH08067
AAH09437
AAH20116
AAH34272
BAB14223
CAI42155
CAI42156
CAI42657
CAI42658
CAI42997
CAI42998
CAI46112
EAX02831
EAX02836
EAX02837
EAX02838
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