Version 5.4
Homo sapiens Protein: EYA2
Summary
InnateDB Protein IDBP-79467.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EYA2
Protein Name eyes absent homolog 2 (Drosophila)
Synonyms EAB1;
Species Homo sapiens
Ensembl Protein ENSP00000321590
InnateDB Gene IDBG-79457 (EYA2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 9 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004725 protein tyrosine phosphatase activity
Biological Process
GO:0007275 multicellular organismal development
GO:0014706 striated muscle tissue development
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
Protein Structure and Domains
PDB ID
InterPro IPR006545 EYA domain
IPR023214 HAD-like domain
PFAM PF00702
PF08282
PF13419
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7ETN2
UniProt Splice Variant
Entrez Gene 2139
UniGene Hs.722416
RefSeq
HUGO HGNC:3520
OMIM 601654
CCDS
HPRD 09041
IMGT
EMBL AL049540 AL121776 AL354766 AL359434 AL390211
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca