InnateDB Protein
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IDBP-7948.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SNAP23
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Protein Name
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synaptosomal-associated protein, 23kDa
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Synonyms
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HsT17016; SNAP-23; SNAP23A; SNAP23B;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000249647
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InnateDB Gene
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IDBG-7946 (SNAP23)
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Protein Structure
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Function |
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
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Subcellular Localization |
Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Note=Mainly localized to the plasma membrane.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. Highest levels where found in placenta.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 69 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
69
[view]
|
Protein-Protein |
68
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000727
Target SNARE coiled-coil domain
IPR000928
SNAP-25
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PFAM |
PF05739
PF00835
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PRINTS |
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PIRSF |
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SMART |
SM00397
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TIGRFAMs |
|
Modification |
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SwissProt |
O00161
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PhosphoSite |
PhosphoSite-O00161
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TrEMBL |
H3BV99
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UniProt Splice Variant |
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Entrez Gene |
8773
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UniGene |
Hs.728237
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RefSeq |
NP_003816
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HUGO |
HGNC:11131
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OMIM |
602534
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CCDS |
CCDS10087
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HPRD |
03962
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IMGT |
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EMBL |
AC018362
AJ011915
AJ278972
AJ278973
AJ278974
AK290152
AK313161
BC000148
BC003686
BC022890
BT006916
CH471125
CR457212
U55936
Y09567
Y09568
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GenPept |
AAC50537
AAH00148
AAH03686
AAH22890
AAP35562
BAF82841
BAG35979
CAA09864
CAA70760
CAA70761
CAC07504
CAG33493
EAW92556
EAW92558
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